Diagnostic accuracy of cytology and colposcopy in cervical squamous intraepithelial lesion : a four - year experience in Hospital University Sains Malaysia

Mohamed Tarmizi, Mohamed Hatta (2001) Diagnostic accuracy of cytology and colposcopy in cervical squamous intraepithelial lesion : a four - year experience in Hospital University Sains Malaysia. Masters thesis, Universiti Sains Malaysia.

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Abstract

OBJEKTIF: Kajian dijalankan untuk menilai ketepatan diagnostik sitologi dan kolposkopi pada wanita yang mempunyai lesion intraepithelium di pangkal rahim dengan mengunakan histologi sebagai 'stan dad emas'. Kami juga mengira sensitiviti, spesifisiti, nilai-nilai ramalan positif dan negatif sitology dan kolposkopi berbanding dengan histologi dalam memastikan keujudan lesion grad tinggi. Tujuan kedua adalah untuk mengenal pasti faktor-faktor berisiko yang mengaitkan wanita yang dikaji dengan Pap smear yang bergrad tinggi. METODOLOGI: Satu kajian garis lintang melibatkan seramai seratus dua belas wanita yang mempunyai sitologi pangkal rahim yang tidak normal dikaji selama empat tahun dari Jun 1997 hingga Mei 2001. Mereka semuanya telah menjalani ujian kolposkopi di Hospital Universiti Sains Malaysia, Kelantan. Satu analisa korelasi diantara sitologi dan kolposkopi dengan gambaran kolposkopi dan histologi telah di buat. Kolposkopi telah dilakukan oleh para ginaekologi di jabatan kami. OBJECTIVE: To evaluate the diagnostic accuracy of cytology and colposcopy in women with cervical intraepitheliallesion using histology as the 'gold standard'. We aim to determine the sensitivity, .specificity, positive and negative predictive values of cytology and/or colposcopy against histology in determining high-grade lesions. Secondly, to identify the possible risk factors for abnormal cytological smear of high-grade lesions in the population studied. STUDY DESIGN: A four-year cross sectional study from June 1997 to May 2001 was conducted in 112 women with abnormal cervical cytology who had undergone colposcopic examination in Hospital University Sains Malaysia. The correlation between cytology and colposcopic impression to colposcopically directed biopsy were analysed. The correlation was accepted accurate when both reports were either the same as histopathological diagnosis.

Item Type: Thesis (Masters)
Subjects: R Medicine > RG Gynecology and obstetrics
Divisions: Kampus Kesihatan (Health Campus) > Pusat Pengajian Sains Perubatan (School of Medical Sciences)
Depositing User: Mr Noorazilan Noordin
Date Deposited: 18 Aug 2017 01:33
Last Modified: 18 Aug 2017 01:33
URI: http://eprints.usm.my/id/eprint/36177

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