Mohamed Tarmizi, Mohamed Hatta
(2001)
Diagnostic accuracy of cytology and colposcopy in cervical squamous intraepithelial lesion : a four - year experience in Hospital University Sains Malaysia.
Masters thesis, Universiti Sains Malaysia.
Abstract
OBJEKTIF: Kajian dijalankan untuk menilai ketepatan diagnostik sitologi dan
kolposkopi pada wanita yang mempunyai lesion intraepithelium di pangkal
rahim dengan mengunakan histologi sebagai 'stan dad emas'. Kami juga
mengira sensitiviti, spesifisiti, nilai-nilai ramalan positif dan negatif sitology
dan kolposkopi berbanding dengan histologi dalam memastikan keujudan
lesion grad tinggi. Tujuan kedua adalah untuk mengenal pasti faktor-faktor
berisiko yang mengaitkan wanita yang dikaji dengan Pap smear yang bergrad
tinggi.
METODOLOGI: Satu kajian garis lintang melibatkan seramai seratus dua
belas wanita yang mempunyai sitologi pangkal rahim yang tidak normal dikaji selama empat tahun dari Jun 1997 hingga Mei 2001. Mereka semuanya telah menjalani ujian kolposkopi di Hospital Universiti Sains Malaysia, Kelantan. Satu analisa korelasi diantara sitologi dan kolposkopi dengan gambaran kolposkopi dan histologi telah di buat. Kolposkopi telah dilakukan oleh para ginaekologi di jabatan kami.
OBJECTIVE: To evaluate the diagnostic accuracy of cytology and
colposcopy in women with cervical intraepitheliallesion using histology as the
'gold standard'. We aim to determine the sensitivity, .specificity, positive and
negative predictive values of cytology and/or colposcopy against histology in
determining high-grade lesions. Secondly, to identify the possible risk factors
for abnormal cytological smear of high-grade lesions in the population studied.
STUDY DESIGN: A four-year cross sectional study from June 1997 to May
2001 was conducted in 112 women with abnormal cervical cytology who had
undergone colposcopic examination in Hospital University Sains Malaysia. The correlation between cytology and colposcopic impression to colposcopically directed biopsy were analysed. The correlation was accepted
accurate when both reports were either the same as histopathological diagnosis.
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