Studying the role of periplasmic chaperones in Fab presentation on phage surface.

Lim , Theam Soon Studying the role of periplasmic chaperones in Fab presentation on phage surface. Project Report. Universiti Sains Malaysia. (Submitted)

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Abstract

In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen binding) fragments during phage display is largely due to the complexity of disulphide bond formation

Item Type: Monograph (Project Report)
Subjects: R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
Divisions: Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM)
Depositing User: Mr Erwan Roslan
Date Deposited: 28 Mar 2017 15:35
Last Modified: 14 Aug 2017 14:43
URI: http://eprints.usm.my/id/eprint/32560

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