Muhammad Yusuf, Muhammad Yusuf
(2015)
Molecular Dynamics Studies
Of The Effects Of Neuraminidase
Mutation On Oseltamivir Resistance.
PhD thesis, Universiti Sains Malaysia.
Abstract
Peningkatan laporan mengenai virus influenza yang resistan terhadap
oseltamivir (OTV) (contohnya mutasi H274Y pada neuraminidase, NA) telah menarik
banyak perhatian para penyelidik. Banyak kajian telah dilakukan untuk memahami
mekanisme rintangan OTV pada NA H274Y.
The increased number of reports on oseltamivir (OTV) resistant strains of
influenza virus (e.g. H274Y mutation on its neuraminidase, NA) has created some
causes for concern. Many studies have been conducted to uncover the mechanism of
OTV resistances in H274Y NA.
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