Structure Prediction And Scfv Design For Bmr1 Antigen Of Brugia Malayi

Khor , Bee Yin (2014) Structure Prediction And Scfv Design For Bmr1 Antigen Of Brugia Malayi. Masters thesis, Universiti Sains Malaysia.

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    Abstract

    Filariasis limfatik yang disebabkan oleh salah satu cacing filaria, Brugia malayi, telah dikenalpasti oleh Badan Kesihatan Sedunia untuk dihapuskan sejak tahun 1997. Antigen rekombinan daripada B. malayi (BmR1) telah menunjukkan spesifisiti dan sensitiviti yang tinggi dalam ujian pengesanan antibodi terhadap filariasis brugian (Brugia Rapid). Maka, antigen ini merupakan calon yang unggul untuk pembangunan ujian pengesanan antigen untuk melengkapkan Brugia Rapid. Lymphatic filariasis which is caused by one of the filarial nematode, Brugia malayi, has been identified by World Health Organization for elimination since year 1997. The recombinant antigen from B. malayi (BmR1) was found to be highly specific and sensitive in the antibody detection test against brugian filariasis (Brugia Rapid).

    Item Type: Thesis (Masters)
    Subjects: R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
    Divisions: Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM) > Thesis
    Depositing User: Mr Firdaus Mohamad
    Date Deposited: 10 Jan 2017 14:33
    Last Modified: 05 Apr 2017 14:12
    URI: http://eprints.usm.my/id/eprint/31509

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