Kuppan, Nithianantham
(2005)
Kajian Ke Atas Aktiviti Antimikrob Ekstrak
Tumbuhan Phyllanthus Niruri (L) Dan
Wedelia Chinensis (Osbeck) Merr.
Masters thesis, Universiti Sains Malaysia.
Abstract
Penyelidikan ini bertujuan untuk mengkaji aktiviti antimikrob daripada pelbagai spesies' .
tumbuhan tempatan. Dalam kajian ini, 8 spesies tumbuhan telah diekstrakkan dengan
menggunakan pelarut organik etanol, metanol, heksana serta air. Kesemua ekstrak ini .
dirawat ke atas 22 spesies mikroorganisma patogen iaitu 10 spesies bakteria, 3 yis dan
9 kulat. Ekstrak metanol daun Wedelia chinensis memberikan kesan perencatan aktiviti
antibakteria (Bacillus cereus) dan anti yis (Candida albicans) yang terbaik dan turut
mencatatkan nilai MIC, 3.12 mg/ml dan 12.50 mg/ml, masing-masing. Ekstrak inijuga
menunjukkan nilai MBC terendah terhadap Bacillus cereus (6.25 mg/ml) dan Candida
albicans (25.00 mg/ml) berbanding tumbuhan lain.
The aim of this study was to investigate the antimicrobial activity from various spesies of
local plants. In this research 8 species of plants were extracted by organic solvents i.e
ethanol, methanol, hexane and water. All of the crude extracts obtained were treated on 22
spesies of pathogens i.e 10 species of bacteria, 3 yeasts and 9 pathogenic fungi. The
methanol leaf extract of Wedelia chinensis showed the best antibacterial (B. cereus) and
antiyeast (c. albicans) activities by giving MIC value of 3.12 mg/ml and 6.25 mg/ml for
B. cereus and C. albicans, respectively, compared to other plant extracts.
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