Regulation Of Telomerase Reverse Transcriptase (Tert) By The Leukaemic Fusion Gene Aml1/Eto

Moses, Emmanuel Jairaj (2015) Regulation Of Telomerase Reverse Transcriptase (Tert) By The Leukaemic Fusion Gene Aml1/Eto. PhD thesis, Universiti Sains Malaysia.

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Abstract

Translokasi kromosom t (8; 21) adalah suatu aberasi kromosom yang biasa berlaku dalam penyakit akut mieloid leukaemia (AML) de novo. Kebarangkalian translokasi ini berlaku dalam AML adalah sebanyak 15%. The chromosomal translocation t(8;21) is a common chromosomal aberration that occurs in up to about 15% of all de novo acute myeloid leukaemia (AML) cases. This translocation results in the formation of a fusion onco-protein known as AML1-ETO (also known as AML1/MTG8, RUNX1/ETO or RUNX1/RUNX1T1).

Item Type: Thesis (PhD)
Subjects: R Medicine > R Medicine (General)
Divisions: Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute) > Thesis
Zoom Profil Pakar (Expert Profile) > Dr. Emmanuel Jairaj Moses (Advanced Medical & Dental Institute)
Depositing User: Mr Noorazilan Noordin
Date Deposited: 01 Sep 2016 04:05
Last Modified: 12 Apr 2019 05:25
URI: http://eprints.usm.my/id/eprint/30436

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