Mohammad Abu-Hashem, Muhannad Abdul-Qader
(2015)
Filtered Distance Matrix For
Constructing High-Throughput
Multiple Sequence Alignment On
Protein Data.
PhD thesis, Universiti Sains Malaysia.
Abstract
Urutan Penjajaran Berganda (MSA) adalah satu proses yang penting dalam biologi
pengkomputeran dan bioinformatik. MSA optima adalah masalah NP-keras
sementara membina penjajaran optimum menggunakan pengaturcaraan dinamik
merupakan masalah NP lengkap.
Multiple sequence alignment (MSA) is a significant process in computational
biology and bioinformatics. Optimal MSA is an NP-hard problem, while building
optimal alignment using dynamic programming is an NP complete problem.
Although numerous algorithms have been proposed for MSA, producing an efficient
MSA with high accuracy remains a huge challenge.
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