Investigating the anti-tuberculosis property of Pluchea indica (beluntas) and Angiopteris evecta (paku gajah) using surrogate organisms.

Mohamad, Suriyati (2017) Investigating the anti-tuberculosis property of Pluchea indica (beluntas) and Angiopteris evecta (paku gajah) using surrogate organisms. Technical Report. Universiti Sains Malaysia.

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Abstract

Pluchea indica and Angiopteris evecta have been used widely in traditional medicine to treat a variety of illnesses including symptoms of tuberculosis (TB) and thus, could provide alternative sources of anti-TB compounds. Preliminary in vitro anti-mycobacterial screening of solvent partitions of both plant materials, using tetrazolium microdilution assay showed that the leaf n-hexane of P. indica exhibited the highest inhibitory activity with MIC of 200 pg/mL against M. kansasii. The highest activity for A. evecta was also exhibited by its leaf n-hexane partition with MIC of 50 pg/mL against M. tuberculosis H37Rv.

Item Type: Monograph (Technical Report)
Subjects: Q Science > QH Natural history > QH1 Natural history (General - Including nature conservation, geographical distribution)
Divisions: Pusat Pengajian Sains Kajihayat (School of Biological Sciences) > Monograph
Depositing User: Mr Erwan Roslan
Date Deposited: 16 Oct 2017 12:13
Last Modified: 16 Oct 2017 12:13
URI: http://eprints.usm.my/id/eprint/37138

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