The Profile Of Urinary Th-1 And Th-2 Cytokines In Patients With Lupus Nephritis.

Abstract

Systemic lupus erythematosus (8LE), considered as the prototype of human systemic autoimmune disease, is a chronic life-long disease. It occur secondary to a dysregulated immune system, which, via various cytokine productions, leads to the production of pathogenic autoantibodies and immune complex deposition in multiple organs. Sistemik lupus eritematosus ( SLE), adalah penyakit 'autoimmune' kronik yang dihidapi sepanjang hayat. Ia berlaku kerana kepincangan system ketahanan harlan, yang melalui penghasilan beberapa sitokin, menyebabkan terhasilnya antibodi-antibodi berlebihan yang menyebabkan kerosakan pelbagai organ.