One Step Multiplex RT-PCR For BCR/ABL Gene In Malay Patients Diagnosed As Leukaemia.

H, Rosline and R, Majdan and A, Wan Zaidah and M, Rapiaah and G, Selamah and Baba, A A and Donald, D M One Step Multiplex RT-PCR For BCR/ABL Gene In Malay Patients Diagnosed As Leukaemia. Working Paper. Universiti Sains Malaysia.

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Abstract

BCR/ABL gene is a product derived from translocation of chromosome 22 to chromosome 9. Its presence confers a diagnostic and prognostic value for Chronic Myeloid Leukaemia (CML) and Acute Lymphoblastic Leukaemia (ALL) respectively. The common breakpoints in BCR cluster regions are at b3a2, b2a2 and e1a2 junction. The main aim of this study was to establish a method in detecting the presence of BCR/ABL fusion gene using a One Step Multiplex RT-PCR and to identify types of breakpoints in leukaemia patients in HUSM.

Item Type:	Monograph (Working Paper)
Subjects:	R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research
ID Code:	10648
Deposited By:	Mr Erwan Roslan
Deposited On:	24 Jun 2009 10:01
Last Modified:	24 Jun 2009 10:01

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